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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bb707e3570864e22fb3b927b7d9e0bb2180f8370670871100eb7115a938585e' 
  AND token = 'djix8b5RGlhYlcG89ZMh/JCOAMEc8hnUKYMXl/7IN1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}