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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41016ce3657bb39493194f9d2ffa805ae01ef2f688d3f531791206318c626ae3' 
  AND token = 'nUt4oPiMahLMqQnBNCcgfw5DKXSwL2zP7kXhxuSn4Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}