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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1c0734dfd88c06c8b2b83fcf6294806b862c763d0cbba593f48b844d47021f' 
  AND token = 'mqquTS2UO7t8Xwk58gb8rEIq9gUO4XZW3uIMU+Xje0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}