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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce425cd148a895d6b91af808f88f18954735663b4e46ae66866c23b6fbc07223' 
  AND token = 'RzbhOmxvRsPll/DLNxgtkB3UaflGXW6+HLsd9ybMO1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}