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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6686e1cce0b98cfede711c11413c29cf5b301269340ba8c4a8551c7a0f597182' 
  AND token = 'sNMbndXovh2W2CwtWSXTE/nPXlzp8JzDn3cXCAK3ulY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}