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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82543636edb85ffa87f683741c1b186f005ea6686a3e266361f566275e7b6957' 
  AND token = 'POZKfNNMKEp13rmNtrlaGwPr2TOxhp1i/1SSZ8fBaq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}