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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb56799ba5c379bb811b8e09d2161cdec5e935de35975d23fa6352d873b33582' 
  AND token = 'piwImyNnZhz+ZgdEbmqkaIWfq/h7T3jm4Tyt2YKKO7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}