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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815fa387ec9719b2da3e392aada074d3fff4f977c1b032d6231a0401cfb54342' 
  AND token = '3DYPqqbjmo7/kfSVJKOO04nrkNMf3yIdH2fP79ZYbk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}