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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196754a7cd62be0e43410ff320d236d19312ac881738a01db61dc008e56bb1ed' 
  AND token = 't4LY5hmpE1/nLR5PyYML3HNAC9Lh67qHWd5g8gVM9Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}