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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37add04da8acf46fab9ab433f879d6229d5b55d5dbca3e1067a90c4948d4c2ff' 
  AND token = 'q5sY/Y0G7IOEd9Sk+5DN/CIYSvf8aOkzeo2cA+aNlAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}