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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221e7d50f86d4850a0ffa1d104d2335d4e7f7e0967a6ea5548399191e59c111a' 
  AND token = 'RLscYKDQLcwoTTCfTqB31FwVnlF5xNJkGyF12dNhu40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}