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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb9e3279ff11c08a3a2cfecd7327cc7008f35d827ad1be563adc62190aaf0c4' 
  AND token = 'fB9ON6qTRifnsKh4OTrvIAhHptGsld4JiBNFq2i3KF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}