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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1397539638b72ee0535b3554de59b63248fc5202ada6d2932503a75bce736747' 
  AND token = 'VDqV1uvBLdR0mc5DJJs/6krQ4GuKTg12BN2BAIuiqe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}