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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acbef1304cf90a36f0a380468755104e211e3c398e44cf0d155da1e077d47de' 
  AND token = 'MuEPq1JkpplciLK/ZfS3WelOqVSh68qbPsQXg/s7h0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}