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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19249d73e9f5863d254b8536b202ff606005da2729bee46c986b772b772ab865' 
  AND token = '/JXagIeQK8Z0LmdBV4te0aDH64wtp4uTDwAwe9BhaPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}