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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8533de27fb3459605f66eee8232dd964f3e30270e86ba575dc691f0fff538668' 
  AND token = 'kfKFirnxAQ+8sXPRPdKIo/YW5MDGjl/8DW+/N7FAVOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}