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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc21b43f3e6d4fec9fd3ebb1362cbc933c9c20e0105aff128f622245572e94e' 
  AND token = 'i6RNCgtUnqlGYVvSaKHwGX76HKkz4eb79mtZC8MZMDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}