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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b35b69ab5eb211502f4f0e73232c32e39b2908a30be8caf7701104064488ec88' 
  AND token = 'O0Ibec1snE03cORe9vy0/8+rQnxtZUUaJuYj94Wp3dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}