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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c3e7b07497c8e16ab1e5fa6f2710fce0671f6ff2ea9cc62435f92760a1bb29' 
  AND token = 'XO6v+SwiPJcqFUi7+RJ6dA/5NDWL5NnJc71MtkJz+9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}