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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7cea849289805d43c813e9b2566043cffbcdbad23da9e1bb7cf1e6f97f13bd5' 
  AND token = 'OeQskrg/9uwyZrcoMOQ5hK/2UGTkape4rFBRU43+Q9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}