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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2e12250b2e96973effa4fc2aff970a84da3e7617fcdc38256f4d7235a10e5e' 
  AND token = 'Cma3wGQx5XZ9Fs+bUFwK+Fqq24roPo3ZR0mb3oqKo8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}