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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afd67b33e8639f89eeeb54c58cc7b8a5bc38c12e19edf21fa9481c72c9b61c3' 
  AND token = 'jHajaqf9XqlCGsdqt5hm1jDBgZ+OI9cGMKmyhWLbgBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}