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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af73d1d03b2601d34838405a09d6ed25d7e511c3acc41813261ab49c9198dbe' 
  AND token = 'C0+Zag5ldEMvJxu8T3DN9tYmIK/cCZBkc2VUMo3PeGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}