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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e0ee01424e3595bc6b61fa5a46d11b7aaac8a55a78759da7d6d47e959ee559' 
  AND token = 'SfCcfZytLuICiS1mMo1xq8RQiQCQ5+kf2Kqy4YpIvho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}