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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1868d30804735fb463f4a7289953a7aec9a8bbe353a540a8d7d3c884587cfa' 
  AND token = 'LD+PdV9l84JOdgtrK9lGLhsb+GCMXYR1Pxmm6AlUxAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}