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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0284003c3bf235e18e32d4d0c4f10cac54d9d444a337094fb286e0da23e1277d' 
  AND token = 'V/6UQXEOs4BuIaBVM4nAslViAQEHBAFrjUmeOZp4fHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}