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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da49bc7a01e690c847639b7b8143f88d9152bcc1ecf962deb3144be058dfed16' 
  AND token = '1EYGqfxbj5W1TRN0S+TkDINJHAun+BPHhaq24LWX/P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}