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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3985e4d1487031dfac529dc9c76d76004b02709e84269235a015f54908d7ee1c' 
  AND token = 'RRbSQCd9Vc03V6e6ARU3UjqhQBfz1TE4tMDQaasidbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}