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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180d78b38d3c0a8ac13de7f9d206006338f61e7bf90f052655d6de007aacd651' 
  AND token = 'EMsyM31baO3hlvgREIxx2hhB7CVmAlzQdlHv0mf5ufw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}