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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1851c189e4ed555a45958f6c74823e79dbd6368b49043efb273dc86bedbd67e8' 
  AND token = '+8Rzi52OaU9HmcnBKoSG1eY/T07Cd1fuzB3FI3ORY30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}