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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17e25a21c487fd5166985223e2fcedc1c4400bfd8b36305800da5361dce8cd4' 
  AND token = 'KKkLe23aPSVlarrOgku4bxV61CNMdJIjEIIpK7dhHXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}