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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be890f549155b205dc24c204ea9fe23b5e457d7c419d8d5eb41fc95c3c460d71' 
  AND token = 'P63+7/EaHVXo1MtX+M4++rrriRc1MhrUPoBl3DnIL+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}