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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953cd408bfc35d5fac040d77b9b0d056292ad19ca9a50afd241380509d36a379' 
  AND token = '0a04Xm3T5+h6Zd+DpBSUqaaXic3ELrEsUc8ECtVuvFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}