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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d214d5a4e236faefb6b86c77fb172c1fa1ba937c3fe726462f783fff00721b' 
  AND token = 'NbIe/IhBpjMV+M+RZIvhf+ORJqkWpLcc352C7sR+PMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}