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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f379466e1f15c72ddc0bd86d6aec5d6be1684508f1241b4b9b0a4ed3e986c26e' 
  AND token = '3iqD5PTSrlcDWV0GEgQDRh7iU1gR1UjzQFzvgHCEOro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}