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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3303c98f3b960ccbe1f42c171eeb209e4cbe10b3957d75ffe7e99f67c209a67b' 
  AND token = '2dxHKEXzeq7xRa057+PiS2Yu5/+DGuvb/bP5U4GxlZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}