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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a80e92c600810ba9bd051161f6aab3cff14e5e4cca74b8baa7efe13c81a347' 
  AND token = 'sUx8xzsrpIl0+77b3CtxhbPVXTPz7yxqHei1eowtdTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}