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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8d21549bd47405c0748564f7a8661a26bd95f5a329efc99be08d283b6e530f' 
  AND token = 'yBle81BBHRTkQWfb2UMoP9dA63mTVt0lxeXw4PeEuVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}