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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21c9b4d86ccaff2d6f7dc2ae0fa1b497fcdfc593451beb026841cd10444e6a4' 
  AND token = 'hrz0gz2TmqWwkQKag/J8fLCsNclS8ivT8pX2D9Mj0+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}