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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c47bee0b99f40cc0f98073589bd0ef23635c842797f6935641c743265c323701' 
  AND token = 'jicwVPARuVWlt73i7TBWqGOkLTqilWiDT88AM2qRCvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}