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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13066a8deb51a4eb93d97a15cb2f2b3357a9b375a7da96df613f71a7d9e47176' 
  AND token = 'iCFpmLcy7CyESiye1Of6qCYcPwRe1yXZly7xTSBqSI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}