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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17eb8018ec814353c562dfec8dafa9eecb92cce88596ef6aac9da033ad6a1546' 
  AND token = '1U1t+NxCVAP/84zC1+EbHb4FsyLHbyIrsGWFxuU+s1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}