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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a43ca2f069f558e8dfc2caf5108225cc645731f56cfa7008dba918f9d3a9b5' 
  AND token = 'TzP6n8s8TFQCeh+44gkXfHsJrgiI/9TB8kvhS2NWGTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}