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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0655db142aa826af000a3a875be1b762d5d35abae94922c080d66d8380a56721' 
  AND token = 'eXFczQmRTZx1f3u7e4RzT06uvvzI54pNGsipAxhyjjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}