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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2d572931c77e249b88b2df702c0c0e72a80163be31f29c81ef980f1bed0302' 
  AND token = 'YuRNuFQreZRhSbVmPMyQWQla4VZjPa1k3/jAg5EM31Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}