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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53df161f91f12625f16c570e8c858ad19b1201f62e4a99007c62fd9be720f168' 
  AND token = 'lR+wJ4tVuP8/tU0uMtjw/Fdw0WFchxSsyEHWqP4NFK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}