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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a9f4c510a7ac2380d49760dc4ba28e593e9c7fde14b0f2242df08adcded6ed' 
  AND token = 'UAR4e0fepAJ9XoQU9y3J+2wp2HC3B4WrfIEWqhP/Q3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}