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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312e0d0cd0bd42c113b29d4f6b3b69a3be69b8ccd34443df5e1452d9ca1a2b04' 
  AND token = 'gPRLHN6l6fbqUpwV94VrBgzfrkq9P3Ic9UcgZKYBHLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}