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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a97a9dbe562eb5b3a8ec5308a16eae5ddc64a53a52f11d3580463040d95afe2' 
  AND token = 'AVwULGpQqIqb4wToIwa+8bu5gA3Ju8Bp64Jt9dG8TuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}