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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6e06a3d91053bfdcc1d1c66e310680699a5701a971dc28431c7832bb860dfc' 
  AND token = 'FHAN1lD4Eyz52wT+AOplNLk9VlQR5jsz9FmXtBF8sx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}